Īny further etiological risk factors not categorized among either transient or persistent subgroups should be labeled as unprovoked venous thromboembolism. Systemic lupus erythematosus and inflammatory bowel disease are among the predisposing medical conditions. However, active cancers and specific medical conditions that increase the risk of venous thromboembolism are categorized as persistent risk factors. It should be noted that general anesthesia for longer than 30 minutes and hospitalization for longer than 72 hours is considered the transient risk factors of DVT. lower extremity injury with limited mobility for more than 72 hours. Accordingly, transient risk factors are as follows 1. Potential risk factors of deep vein thrombosis might be categorized according to the transient, persistent or unprovoked criteria. Both factors, associated with disorders in several coagulation factors, favor the appearance of venous thrombosis, thrombophlebitis, and thromboembolic events, and mostly fatal pulmonary thromboembolisms (PE), which are the primary cause of mortality in obese patients. slower venous circulation flow in the infra diaphragmatic and especially in the lower limbs. increased fibrinogen levels that may even surpass twofold the normal value, and 2. Obesity is associated with a hypercoagulability status via two mechanisms, 1. Obesity, pregnancy, the advanced age of older than 60, surgery, critical care admission, dehydration, and cancer are the established causalities of DVT and VTE. Only through early diagnosis and treatment can the morbidity be reduced.Īcquired: Cancer, sepsis, myocardial infarction, heart failure, vasculitis, systemic lupus erythematosus and lupus anticoagulant, Inflammatory bowel disease, nephrotic syndrome, burns, oral estrogens, smoking, hypertension, diabetes ĭeep-vein thrombosis is a major medical problem accounting for most cases of pulmonary embolism. Even in patients who do not get pulmonary emboli, recurrent thrombosis and "post-thrombotic syndrome" are major causes of morbidity. It is part of the venous thromboembolism disorders, representing the third most common cause of death from cardiovascular disease after heart attacks and stroke. Deep-vein thrombosis is a common and important disease. Ī deep-vein thrombosis (DVT) is a blood clot that forms within the deep veins, usually of the leg, but can occur in the arms and the mesenteric and cerebral veins. The rate of particular site involvement depends on the anatomical location as follows, distal veins 40%, popliteal 16%, femoral 20%, common femoral 20%, and iliac veins 4%. It is a common venous thromboembolic (VTE) disorder with an incidence of 1. DVT usually involves the lower limb venous system, with clot formation originating in a deep calf vein and propagating proximally. Deep vein thrombosis (DVT) is an obstructive disease with hindering venous reflux mechanism.
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